Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9908 | CA24469 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 100 |
| 2 | 3TC+AZT | 39 |
| 3 | DDI+NVP+TDF | 243 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | V60I, R83K, V90I, D123E, S162Y, N175Y, T200A, K201I, L228H, K277R, A288S, I293V, E297A |
| >CA24469| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKKTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQYPDIVI YQYVDDLYVGSDLEIGQHRAIIEELRQHLLRWGFTTPDQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKSLTEVVPLTAEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L24I | L10I, K14R, L19I, L63P, I64V, A71T, I93L |
| >CA24470| codons 1-98 PQITLWQRPIVTIRIGGQIKEALIDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPVEICGHKTIGTVLVGPTPANIIGRNLLTQLGCTLN |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |