Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9902 | CA24449 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | 69 |
| 2 | 3TC+D4T+EFV | 31 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, Q151M, M184V | D67G, K70H, K219R | K101E, Y181C, G190AS | K82R, I142V, S162AD, R211K, A272P, K277R | K30R |
| >CA24449| codons 1-304 PISPIETVPVKLKPGMDGPKVKQWPLTEERIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKGSTHWRKVVDFRELNRRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPMGWKGSPAIFQASMTKILEPFRKQNPDIVI CQYVDDLYVASDLEIGQHRTKIEELRQHLLKWGFTTPDRKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAE LELA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19I, N37S, P39PQ, L63P |
| >CA24450| codons 15-99 IGGQIKEALLDTGADDTVLEEMSLQGRWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGT VLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |