<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
R74018 R74018 Thailand 2008 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, G16E, K20I, E35N, M36I, R41K, Q61E, L63P, H69K, K70R, I72V, L89M  
>R74018| codons 1-99
PQITLWQRPLVTVKVEGQLIEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVRQYD
EIPIEICGKRAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  V75L     E6EK, K11T, V35T, T39K, K43E, T69TS, K101KR, K102R, K104KR, K122E, D123S, I135T, S162SC, T165I, K173L, Q174K, D177E, I178IL, V179T, T200I, Q207A, R211S, I244V, V245N  
>R74018| codons 1-257
PISPIKTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSSKWRKLLDFRELNKRTQDFWEVQLGIPHPAGLRRKRSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMIKILEPFRLKNPELTI
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPVNLPEKDSWTVNDI

References
Author Title Citation
Kiertiburanakul, S Comparisons of primary HIV-1 drug resistance between recent and chronic HIV-1 infection within a sub-regional cohort of Asian patients. PLoS ONE, 2013