<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA1506 CA24407 U.S. 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 52
2 DDC 554

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M       V35X, T39A, T69X, K102Q, A158AS, S162A, T165I, I167IV, G196K, L228H, S251N, K277R, L283LI, I293V, E297A V111L
>CA24407| codons 1-300
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALXEICAEMEKEGKISKIGPENPYNTPV
FAIKKKDSXKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDLGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPSIFQASMIKVLEPFRKQNPDIVI
YQYMDDLYVGSDLEIKQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDNWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGTKALTEVVPLTAEAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15IV, L63P  
>CA24408| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Gonzales, MJ Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. AIDS, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005