<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA9869 CA24334 U.S. 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 74
2 DDI 56
3 3TC+AZT+NVP 252

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y K219N K101E, Y181C   K20R, V35L, T39A, K43Q, E44D, V60I, A98S, I135R, I167V, V179I, G196E, I202V, R211K, D218E, H221Y, A272P, T286P, I293V, E297A  
>CA24334| codons 1-300
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICAELEQDGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLEKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKVLEPFRKQNPDIII
CQYVDDLYVGSDLEIEQHRTKVEELRQHLWKWGFYTPENKYQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGPKALTEVVPLTAEAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12I, I13V, K20KM, I62IV, L63P, A71AT  
>CA24335| codons 1-99
PQITLWQRPLVIVKIGGQLMEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005