<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
X12025 X12025 Hong Kong 2007 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, G16E, L19I, E35EK, M36I, R41K, R57K, L63V, H69K, T74A, L89M, I93L D29DN, G40GE, R87RK
>X12025| codons 1-99
PQITLWQRPLVPIKIEGQIKEALLDTGANDTVLEKINLPEKWKPKMIGGIGGFIKVKQYD
QIVIEICGKKAIGAVLVGPTPVNIIGKNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36EA, T39D, S48T, V60I, K104R, D121H, K122E, I135R, E169D, K173A, Q174QK, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, I326V, Q334N, G335D, I341IV, G359T, T377M, K390R, A400T  
>X12025| codons 1-401
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGNDQWTYQVYQEPFKNLKTGKYARMRTA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETW

References
Author Title Citation
Kiertiburanakul, S Comparisons of primary HIV-1 drug resistance between recent and chronic HIV-1 infection within a sub-regional cohort of Asian patients. PLoS ONE, 2013