Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9851 | CA24261 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | 135 |
| 2 | None | 61 |
| 3 | 3TC+ABC+DLV+LPV | 83 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L10FI, L24LI, L33LF | K20X, E35D, M36I, R41RK, R57K, L63P, A71V, I93L |
| >CA24261| codons 1-99 PQITLWQRPFVTIKIGGQLXEALIDTGADDTVFEDINLPGKWKPKLIGGIGGFVKVKQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74I, M184V | K103KN, Y181C | K11KR, K20R, T39E, K166R, I202V, Q207E, R211K, A272P, K277R, T286A, E302D | Y232YH |
| >CA24260| codons 1-302 PISPIETVPVRLKPGMDGPRVKQWPLTEEKIKALVEICEEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI CQYVDDLYVGSDLEIGQHRTKVEELREHLLKWGFTTPDKKHQKEPPFLWMGHELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTEEAE LD |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |