<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+D4T+EFV 26
3 AZT+DDI+LPV 209

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215TFIS   K103N, M230ML   V21VI, V35T, T39E, E42EK, E44EK, S48T, V60I, T69TA, K122E, D123G, E138EG, K173AT, Q174K, D177E, T200A, I202V, Q207QK, R211K, V245Q  
>3026| codons 1-262
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICEEMKKKGKITKIGPENPYNTPI
FAIKKKDSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNGTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKVEELRKHLLKWGFSTPDKKHQKEPPFLWLGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV, V82VA G48GE T12S, I15IV, L19V, K20R, E35D, M36I, N37D, Q61E, I62IV, L63T, E65D, H69K, A71AV, I72V, T74S, L89M, I93L  
>3026| codons 1-99
PQITLWQRPLVSIKVGGQVREALLDTGADDTVLEDIDLPGRWKPKMIEGIGGFVKVRQYD
EVTIDICGKKVVGSVLVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013