<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69DN, K70R, M184V K219Q K103N, M230L V108I, L234I V35T, E36A, T39E, S48T, K122E, D123G, S163A, M164X, K173A, D177E, I178IM, T200A, Q207A, R211RK, H221Y, L228R, V245Q S162V
>951| codons 1-254
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQVAXTKILEPFRAQNPEMVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDQKYQKEPPFRWLGYEIHPDKWT
VQPIQLPEKDSWTV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19T, K20R, M36I, P39S, R41K, I62V, H69K, L89M, I93L  
>951| codons 1-99
PQITLWQRPLVTIKVGGQTREALLDTGADDTVLEEINLSGKWKPKMIGGIGGFIKVRQYD
QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013