<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L76V, V82A   L10V, T12TS, I15V, L19I, K20R, M36I, N37D, K55R, R57RK, D60E, I62V, L63P, H69K, A71V, L89M, I93L  
>326| codons 1-99
PQITLWQRPVVSIKVGGQIREALLDTGADDTVLEEIDLPGRWKPKMIGGIGGFVRVKQYE
QVPIEICGKKVIGTVVVGPTPANIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70KR, M184V       K20KR, E28K, K32E, V35T, E36A, T39E, S48ST, K122E, D123GS, I135T, K173T, D177E, V179VI, T200A, Q207E, V245K  
>326| codons 1-252
PISPIETVPVKLKPGMDGPRVKQWPLTKEKIEALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIII
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSW

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013