<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+ABC+D4T+NVP 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, L74V, M184V K219Q Y181C, G190A   V35I, T39E, S48T, K122E, D123G, I135V, I142V, K173A, Q174K, D177E, I178M, T200A, E203K, Q207E, V241I, V245Q, D250N, S251N, N255Y K263Q
>340| codons 1-263
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICEEMEKEGKITKIGPENPYNTPV
FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEMVI
CQYVDDLYVASDLEIGQHRAKIKELREHLLRWGFTTPDQKHQKEPPFLWMGYELHPDKWT
IQPIQLPEKNNWTVYDIQKLVGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L10F T12S, I15V, L19I, R41K, L63P, H69K, V77I, I93L  
>340| codons 1-99
PQITLWQRPFVSIKVGGQIKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFVKVRQYD
QIPIEICGKKAIGTVLIGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013