<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N   P4S, K20R, V35T, E36A, T39E, S48T, T165I, T200A, Q207D, R211K, F214L, L228R, V245K  
>1722| codons 1-254
PISSIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGLTTPDKKHQKEPPFRWMGYELHPDKWT
VQPIKLPEKDSWTV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  Q58E L10I, T12S, K14I, I15V, L19R, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, V77I, I93L  
>1722| codons 1-99
PQITLWQRPIVSIIVGGQRKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVREYE
EIPIEICGKKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013