Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5976 | CA24143 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 61 |
| 2 | 3TC+AZT+RTV+SQV | 57 |
| 3 | 3TC+AZT+NFV | 113 |
| 4 | ABC+APV+D4T | 31 |
| 5 | Unknown | 77 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, I84V, L90M | L10I, K20R, E35D, M36I, R41K, I62V, L63P, I64V, A71T, I93L |
| >CA24143| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYD QVPVEICGHKTIGTVLVGPTPANVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, L210W, T215Y | D67G | S68G, V118I, I142V, Q207E, R211K, D218E, K219T, I257L, K277R, T286A, I293V, E297K |
| >CA24142| codons 1-302 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKGGTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPETKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDLQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVVPLTKEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |