<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+DDI+LPV 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16E, L19I, E35D, M36I, R41K, D60E, H69K, L89M, I93L  
>756| codons 1-99
PQITLWQRPLVSIKVEGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, T215Y K219Q K103N, V106M, Y188H   V35T, E36A, T39E, V60I, K102R, K122E, D123S, I135V, I142T, T200A, E203K, Q207E, R211K, F214L, K223T, L228R, V245Q  
>756| codons 1-262
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRNKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSVNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLHVGSDLEIGQHRAKIKELREHLLKWGLYTPDQKHQTEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVG

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013