<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115YF, M184V   L100I, K103N P225H V35T, T39E, S48T, V60VI, K104R, K122E, D123S, I135T, E138A, T139A, K173T, Q174K, D177N, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D  
>1068| codons 1-252
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNRSVTVLDVGDAFFSVPL
DESFRKYTAFTIPSTNNAAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPNIVI
YQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIQLPDKDSW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  Q58E T12S, I13V, I15V, L19I, E35D, M36I, R41K, R57RK, Q61E, L63P, H69K, I72IV, T74S, V82VI, L89M, I93L  
>1068| codons 1-99
PQITLWQRPLVSVKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKEYD
EIPIEICGKKAVGSVLVGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013