Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9813 | CA24125 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | 261 |
| 2 | 3TC+D4T+IDV+NFV | 70 |
| 3 | 3TC+D4T+NVP+SQV | 15 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | G73S | L10I, T12TA, I15V, R41K, K55R, L63P, A71V, I93L |
| >CA24125| codons 1-99 PQITLWQRPIVAIKVGGQLKEALLDTGADDTVLEEMNLPGKWKPKLIGGIGGFVRVRQYD QIPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K103N, Y181C | T7P, K43Q, K122P, I135T, D177DE, I178IL, V179I, G196E, H208HY, L228H, Q242QH, T286A, I293IV, E297K |
| >CA24124| codons 1-300 PISPIEPVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPELII CQYVDDLYVGSDLEIEQHRTKIEELRQYLWRWGFYTPDKKHQKEPPFHWMGYELHPDKWT VHPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTKEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |