<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F D67G V106M, Y181C, G190S   V35T, E36A, T39E, V60I, W88C, K122E, D123N, S134SN, E169EK, K173T, Q174K, D177EK, I178M, E194EK, I195L, R199RK, T200A, E203EK, Q207A, R211K, V245EK, E248EK R143RK, Q145Q*
>469| codons 1-255
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPI
FAIKRKGSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSMTVLDVGDAFFSVPL
DENFRKYTAFTIPNINNETPGIKY*YNVLPQGWKGSPAIFQSSMTKILKPFRTKNPKMVI
CQYMDDLYVSSDLKLGQHKAKIKELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPKKDSWTVN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, L63Q, H69K, T74S, L89M, I93L  
>469| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIQIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013