<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219E K101E, K103N, G190A   K20KR, E28K, K32E, V35K, E36A, T39E, S48T, V60I, W88S, V90I, K122E, D123G, I135V, S162H, K173A, D177E, I178L, T200A, E204K, Q207D, R211K, V245Q, E248D  
>1276| codons 1-255
PISPIETVPVKLKPGMDGPRVKQWPLTKEKIEALKAICEEMEKEGKITKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFSEIQLGIPHPAGLEKNKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRAQNPELVI
YQYVDDLYVASDLEIGQHRAKIEKLRDHLLKWGFFTPDEKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, K14R, I15V, L19I, K20R, E35D, M36I, N37D, R41K, H69K, I72IM, T74S, L89M, I93L  
>1276| codons 1-99
PQITLWQRPLVSIRVGGQIREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAMGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013