<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 AZT+DDI+LPV 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, L89I, I93L A22D, A71D
>50| codons 1-99
PQITLWQRPLVSIKVGGQIKEDLLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
EIPIEICGKKDIGTVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179D P4S, V8I, V35T, T39E, S48T, K102Q, K103R, K122E, I159IV, K173A, D177E, G196T, T200A, Q207E, R211K, L228I, V245EK, E248D, D250E, A272P, K277N, Q278R, E291D, I293V, P294T, S322SL, Q334N, G335D Q258P, Q340Q*
>50| codons 1-342
PISSIETIPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQRKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAVFQSSMTKILEPFRAQNPEIDI
YQYMDDLYVGSDLEITQHRAKIEELREHLLKWGFTTPDKKHQKEPPFIWMGYELHPDKWT
VQPIKLPDKESWTVNDIPKLVGKLNWASQIYPGIKVNRLCKLLRGTKALTDVVTLTEEAE
LELAENREILKEPVHGVYYDPLKDLIAEIQKQGNDQWTY*IY

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013