<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+LPV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R   K103N, Y181C, G190A   P14A, K20R, V35T, E36A, T39E, E40D, S68N, W88C, K101Q, K122E, D123N, I135T, I142V, T200A, I202IV, Q207A, R211K, F214L, H221Y, V245L, D250E  
>1824| codons 1-262
PISPIETVPVKLKAGMDGPRVKQWPLTEEKIKALTAICEDMEKEGKISKIGPENPYNTPV
FAIKRKDNTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLQKNKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRAKVEELRAHLLKWGLTTPDKKYQKEPPFLWMGYELHPDKWT
VQPILLPEKESWTVNDIQKLVG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16E, L19I, K20R, E35D, M36I, P39Q, R41K, D60E, Q61QE, L63AV, H69K, L89M, I93L  
>1824| codons 1-99
PQITLWQRPLVSIKVEGQIREALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVRQYE
EIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013