<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+DDI+LPV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V K219Q K101E A98G K20R, V35T, T39E, S48T, V60I, K122E, D123N, I135V, E138A, S162C, K173T, Q174KR, V179I, G196E, T200A, Q207K, R211T, D237N, V245Q  
>2453| codons 1-257
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTRNPDIII
YQYVDDLYVGSDLEIEQHRAKIEELRKHLLTWGFTTPDQKHQKEPPFLWMGYELHPNKWT
VQPIQLPEKDSWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A L10F I15V, L19IT, K20R, E35D, M36I, R41K, K55R, D60E, Q61E, I62V, L63P, H69K, A71V, L89M, I93L  
>2453| codons 1-99
PQITLWQRPFVTIKVGGQTREALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVRVRQYE
EVPIEICGKKVIGTVVVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013