<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V K70KQ, K219R V106M, G190A F227L V35R, T39D, S48T, W88C, K122E, D123N, I135T, I142IL, K173A, Q174K, V179I, V189I, Q197E, T200A, I202V, Q207A, R211K, F214L, V245Q  
>3042| codons 1-256
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALREICDEMEKEGKITKIGPENPYNTPV
FAIKKKDSTQWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGLRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIII
YQYVDDLYIASDLEIGEHRAKVEELRAHLLKWGLTTPDRKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKDSWTVND

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19T, K20R, E35D, M36I, N37D, R41K, L63S, H69K, I72IT, L89M, I93L  
>3042| codons 1-99
PQITLWQRPLVTIKVGGQTREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QISIEICGKKATGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013