Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8022 | CA24065 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ SQV | 315 |
| 2 | ABC+D4T+NVP+SQV | 10 |
| 3 | D4T+DDI+DLV | 18 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | L23I, N88D | L10I, I13V, M36I, N37D, L63P, A71V, I72V, T74S |
| >CA24065| codons 1-99 PQITLWQRPIVTVKIGGQLKEAILDTGADDTVLEEIDLPGRWKPKMIGGIGGFVKVRQYD QIPIEICGHKVVGSVLVGPTPVNIIGRDLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K103N | K20R, K43N, T69A, K122E, D123S, I142V, G196E, T200I, P243PS, V245K, S251I, I293V |
| >CA24064| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELENEGKISKIGPENPYNTPV FAIKKKDSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRIKIEELRQHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQSIKLPEKDIWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |