<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 AZT+DDI+LPV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R T215TI, K219Q   E138K V8I, V35T, T39E, S48T, K122E, D123G, I135V, S162C, K173A, Q174K, D177E, T200A, Q207G, R211K, V245Q  
>1248| codons 2-257
ISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPVF
AIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
EGFRKYTAFTIPSVNNKTPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPEIVIY
QYMDDLYVGSDLEIGQHRAKIEELRGHLLKWGFITPDQKHQKEPPFLWMGYELHPDKWTV
QPIQLPEKDSWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82A, L90M L10F, L33F, K43T, G73S T12S, I13V, I15V, L19V, K20R, E35D, M36I, R41K, Q61H, L63P, H69K, K70KR, A71V, I93L  
>1248| codons 1-99
PQITLWQRPFVSVKVGGQVREALLDTGADDTVFEDINLPGKWTPKIIGGIGGFVKVRQYD
HIPIEICGKRVISTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013