<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 AZT+DDI+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, T215F   K103N, V106M, G190A   K32I, V35K, T39D, V60I, K122E, D123S, S162D, E169A, K173A, Q174K, N175Y, D177E, Q197L, T200A, E203D, Q207D, R211K, V245E  
>1724| codons 1-262
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIIALKEICDEMEKEGKISKIGPENPYNTPI
FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILAPFRAKYPEIVI
YQYMDDLYVASDLEIGLHRAKIDELRDHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82M, L90M V11VI, L33F L10V, T12S, I13V, L19I, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63V, I64L, H69K, A71V, T74S, L89M, I93L  
>1724| codons 1-99
PQITLWQRPVISVKIGGQIREALLDTGADDTVFEDIDLPGKWKPKIIGGIGGFVKVKQYD
QVVLEICGKKVIGSVVVGPTPMNIIGRNMMTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013