Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| O861 | 262 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+D4T+EFV+NVP | 26 |
| 2 | AZT+DDI+LPV | 26 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, D60E, Q61E, H69K, L89M, I93L |
| >262| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE EILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123S, A158AS, S162SG, K173AT, D177DN, T200E, Q207KN, R211K, E248ED, D250E |
| >262| codons 1-259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQGSMTKILEPFRTQNPNIVI YQYMDDLYVGSDLEIGQHREKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKESWTVNDIQK |
References
| Author | Title | Citation |
| Van Zyl, GU | Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. | PLoS ONE , 2013 |
| Posada Cespedes, S | Learning evolutionary pathways of HIV-1 subtype C under lopinavir treatment | IAS 2017, 2017 |