<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, I15V, G16E, L19I, K20R, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93L  
>1472| codons 1-99
PQITLWQRPLVPIKVEGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V   V106M V108I, V179D K20R, T27S, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123N, I135L, E138A, K173A, Q174K, D177E, T200A, E203K, Q207E, R211K, F214L, K223T, V245Q P59PS
>1472| codons 1-258
PISPIETVPVKLKPGMDGPRVKQWPLSEEKIKALTAICEDMEKEGKITKIGPENPYNTSI
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTILDVGDAYFSVPL
DENFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIDI
YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGLTTPDKKHQTEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQ

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013