<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 FTC+LPV+TDF 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, L74LV, M184V, T215Y   Y188L A98AG V35IT, E36AD, T39DE, E40EK, S48T, V60VI, V106VI, K122E, D123DN, K173A, D177G, T200A, Q207N, R211K, V245Q K64KHNQ, T128TI, W153W*
>2169| codons 1-257
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICEKLEKEGKITKIGPENPYNTPI
FAIQKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSITVLDVGDAYFSVPL
DENFRKYIAFTIPSINNETPGIRYQYNVLPQG*KGSPAIFQSSMTKILEPFRAQNPGIVI
YQYVDDLLVGSDLEIGQHRAKIEELRNHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12PS, I15V, L19I, M36L, N37S, L63P, H69K, I93L R87RK
>2169| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEELSLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGKNLLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013