<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+D4T+EFV 26
3 3TC+LPV+TDF 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, M184V   L100I, K103N   K20R, V35T, T39G, K49R, D121H, K122E, I135T, T139S, E169D, K173S, Q174K, D177E, T200A, E203ED, Q207DEKN, R211K, F214L  
>1935| codons 1-239
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICGEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSTNNESPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRSKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIDELRNHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, I13V, I15V, G16E, E35D, M36I, R41RK, D60DE, L63S, H69K, K70R, L89IM, T91V, I93L  
>1935| codons 1-99
PQITLWQRPLVPVKVEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
QISIEICGKRAIGTVLVGPTPVNIIGRNMLVQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013