<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 D4T+DDI+LPV 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16E, K20KR, E35D, M36I, R41K, I62IV, L63V, I64L, H69K, I72V, L89M  
>697| codons 1-99
PQITLWQRPLVTIKIEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVVLEICGKKAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KR T215TI, K219KE     P4PT, E6EK, V35T, V60VI, T69TN, V118I, K122E, D123N, I135T, E138EG, I142V, R172RK, K173A, I202V, Q207N, R211K, F214L E29EK
>697| codons 1-224
PISTIKTVPVKLKPGMDGPKVKQWPLTEKKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSTNNGTPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFKAQNPDIVI
YQYMDDLYVGSDLEIGQHRTKVEELRNHLLKWGLITPDEKHQKE

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013