<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+DDI+LPV 26
3 3TC+ABC+AZT 104

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, T215Y   K103N A98G, K238T K20R, V35T, T39E, S117A, K122E, D123S, I135L, E138A, S162CY, K173A, Q174K, Q207E, H208Y, R211K, W212R, V245K, D250E E44Y
>1774| codons 1-257
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEELEKYGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFAVPL
DESFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRAKNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELREYLLKRGFYTPDKKHQKEPPFLWMGYELHPDTWT
VQPIKLPEKESWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E35D, M36I, R41K, R57RK, Y59F, Q61E, L63A, H69K, L89M, I93L  
>1774| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQFD
EIAIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013