<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 AZT+DDI+LPV 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    M36I, R41K, Q61E, I62IV, L63S, H69K, L89M, I93L  
>885| codons 24-99
LDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDEVSIEICGKKAIGTVLVGPTPVN
IIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215F   K103N A98G V35T, T39D, S48T, E53D, K122E, D123S, I135L, S162C, K173A, I178L, G196E, T200A, Q207E, R211K, L228Q, V245Q, E248D  
>885| codons 1-259
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICDEMEKEGKITKIGPDNPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQNPDLVI
YQYMDDLYVGSDLEIEQHRAKIEELREHLLKWGFFTPDKKHQKEPPFQWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQK

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013