<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+LPV+TDF 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11I T12S, I15V, G16E, L19I, R41K, K55R, D60E, L63H, H69K, V77I, L89I, I93L  
>2438| codons 1-99
PQITLWQRPLISIKVEGQIKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIRVRQYE
QIHIEICGKKAIGTVLIGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, M184V, T215TFIS K219E Y181YC   E6D, K20R, V35IT, E36A, T39D, S48T, K122E, D123N, T139A, S162SCT, K166R, Q174N, G196GE, T200E, E203EK, Q207E, R211K, V245Q  
>2438| codons 1-257
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSPAIFQTSMTRILEPFRKNNPDIVI
CQYVDDLYVGSDLEIEQHREKIKELREHLLKWGFSTPDEKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDI

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013