<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+DDI+LPV 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    M36I, R41K, K45R, L63S, H69K, L89I, I93L  
>820| codons 23-99
LLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYDQISIEICGKKAIGTVLVGPTPV
NIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215TFIS   K103N, V106M   P4S, E6EK, K20R, V35T, E36A, T39E, S48T, E53D, K122E, T139TK, S162A, K173A, D177E, I178M, T200A, E204K, Q207E  
>820| codons 1-234
PISSIKTVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPDNPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAQNPEMVI
YQYVDDLYVGSDLEIGQHRAKIEKLREHLLRWGFSTPDKKHQKEPPFLWMGYEL

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013