<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+LPV+TDF 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V K219Q K101E, G190A   P4T, V35T, T39D, S48T, V60I, S68KR, W88C, A98S, V106I, V118I, K122E, D123S, E138A, K173R, Q174K, T200A, Q207E, R211K, F214L  
>2442| codons 1-238
PISTIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICDEMEKEGKITKIGPENPYNTPI
FAIKRKDRTKWRKLVDFRELNKRTQDFCEVQLGIPHPSGLEKKKSITVLDVGDAYFSIPL
DESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPDIVI
YQYVDDLYVASDLEIGQHRAKIEELREHLLKWGLTTPDQKHQKEPPFLWMGYELHPDK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47A L24I T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45R, D60E, I62V, L63P, H69K, V77I, V82I, L89IM, I93L  
>2442| codons 1-99
PQITLWQRPLVSIKVGGQIREALIDTGADDTILEDINLPGKWKPRMAGGIGGFIKVRQYE
QVPIEICGKKAIGTVLIGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013