<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+D4T+EFV 26
3 3TC+AZT+TDF 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219EQ K101E, G190S   E28K, V35T, T39E, K122E, D123S, I142V, K173A, D177E, V179VI, T200A, R211K, V245Q, D250E  
>1527| codons 1-257
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIII
YQYVDDLYVSSDLEIGQHRAKIEELRQHLLKWGFFTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, L19T, E35D, N37IT, Q61E, I62IV, L63P, I64IM, H69K, I72IV, L89M, I93L  
>1527| codons 1-99
PQITLWQRPLVSIKIGGQTKEALLDTGADDTVLEDMTLPGRWKPKMIGGIGGFIKVRQYD
EVPMEICGKKAVGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013