Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5126 | CA23962 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 117 |
| 2 | 3TC+AZT+IDV | 148 |
| 3 | D4T+DDI+EFV | 34 |
| 4 | 3TC+APV+AZT | 94 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219E | E6EK, K20R, V35T, K43E, E44A, V60I, V118I, K122KE, P176Q, V179I, G196E, I202V, H208Y, R211K, I293V, E297P |
| >CA23962| codons 1-300 PISPIKTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTELEEAGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNQDIII YQYVDDLYVGSDLEIEQHRTKVEELRQYLWKWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTPEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, L90M | L33F, G73S, L89V | L10I, I13V, L24F, I62V, L63P, V77I, V82I, I93L |
| >CA23963| codons 1-99 PQITLWQRPIVTVKIGGQLKEALFDTGADDTVFEEMNLPGRWKPKLIGGIGGFIKVRQYD QVPIEICGHKAISTVLIGPTPINIIGRNVMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |