<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+DDI 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V K219Q K101E, K103N, G190A   T27S, V35T, E36A, T39E, V60I, S105T, V118I, I135T, E138A, I142V, K173L, Q174K, V189VI, T200A, R211K, F214L, V245Q E29G
>2118| codons 1-257
PISPIETVPVKLKPGMDGPKVKQWPLSEGKIKALTAICEEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKNKTVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSTNNATPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPDIVI
YQYVDDLYIASDLEIGQHRAKIEELRQHLLKWGLTTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19IT, K20KR, E35D, M36I, R41K, Q61E, L63P, H69K, T74S, L89M, I93L  
>2118| codons 1-99
PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
EIPIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013