Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4409 | CA23930 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 79 |
| 2 | AZT+DDI | 31 |
| 3 | 3TC+AZT+IDV | 74 |
| 4 | APV+D4T+NVP | 9 |
| 5 | DDI+RTV+SQV | 27 |
| 6 | 3TC+D4T | 30 |
| 7 | 3TC+ABC+D4T | 18 |
| 8 | Unknown | 100 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, L210LW | T215TS, K219KE | K103N | V179E, P225PH | K122E, D123E, I135T, S162Y, T200E, R211K, F214FL, L228H, T286A, I293IV, E297K |
| >CA23930| codons 1-299 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIEI YQYVDDLYVGSDLEIGQHREKIEELRQHLWKWGLSTPDEKHQKEHPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTKEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, G16GE, R41RK, I62V, I64V, I72V, V77I |
| >CA23931| codons 1-98 PQITLWQRPLVTVKVEGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QVLVEICGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLN |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |