<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA4409 CA23930 U.S. 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 79
2 AZT+DDI 31
3 3TC+AZT+IDV 74
4 APV+D4T+NVP 9
5 DDI+RTV+SQV 27
6 3TC+D4T 30
7 3TC+ABC+D4T 18
8 Unknown 100

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, L210LW T215TS, K219KE K103N V179E, P225PH K122E, D123E, I135T, S162Y, T200E, R211K, F214FL, L228H, T286A, I293IV, E297K  
>CA23930| codons 1-299
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIEI
YQYVDDLYVGSDLEIGQHREKIEELRQHLWKWGLSTPDEKHQKEHPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTKEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, G16GE, R41RK, I62V, I64V, I72V, V77I  
>CA23931| codons 1-98
PQITLWQRPLVTVKVEGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QVLVEICGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLN

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005