<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+LPV+TDF 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y   K103N V179E, K238T E6K, K20R, V35T, T39E, E44D, S48T, V60I, V118I, K122E, D123N, I135T, E138A, K173T, Q174K, D177N, I178L, T200A, E203K, Q207E, H208Y, R211K, K223E, P243Q, V245Q, E248D, D250E  
>1550| codons 1-258
PISPIKTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEELEKDGKITKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPNLEI
YQYVDDLYVGSDLEIGQHRAKIKELREYLWKWGFYTPDKKHQEEPPFLWMGYELHPDTWT
VQQIQLPDKESWTVNDIQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, I84V   T12S, I13V, I15V, G16E, L19I, K20T, M36I, R41K, K45V, D60E, Q61E, I66V, H69K, K70R, I72V, V82I, L89M, I93L  
>1550| codons 1-99
PQITLWQRPLVSVKVEGQITEALLDTGADDTVLEEINLPGKWKPVMIGGIGGFVKVRQYE
EILIEVCGKRAVGTVLVGPTPINVIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013