<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA9745 CA23909 U.S. 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54M, V82A L33F, Q58E L10I, I13IV, K55R, L63P, A71V, I93L  
>CA23909| codons 1-98
PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMNLPGRWKPKIVGGIGGFMRVREYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLN

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, L74V, Y115F, M184V, T215F K219H G190E A98G V35T, V60I, K101R, D123E, I135T, D177E, R211RK, F214L, K249Q, A288S, I293V, P294V, E297K  
>CA23908| codons 1-299
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLRKKKSVTVLDVGDAFFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYVDDLYVESDLEIGQHRTKIEELRQHLLKWGLFTPDHKHQKEPPFLWMGYELHPDKWT
VQPIVLPEQDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVVVLTKEA

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005