<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, M184V K219KDEN L100I, K103N   V35T, T39E, E40EG, S48T, V60I, W88C, V118I, K122E, D123G, I135R, K173A, Q174K, D177E, G196E, T200A, I202V, Q207A, H208HL, R211K, F214L, K223KE, V245Q, D250E  
>1028| codons 1-259
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEGMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFCEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL
DEGFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVGSDLEIEQHRAKVEELRALLLKWGLTTPDNKHQEEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, Q61E, L63T, H69K, K70R, T74S, L89M, I93L  
>1028| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD
EITIEICGKRAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013