<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, M184I   V106M, Y181C   V35T, E36A, T39E, S48T, V60I, K122E, D123S, T139V, A158S, Q174E, I178L, T200A, Q207E, R211K, F214L, H221Y, D237N, V245Q, D250E  
>2416| codons 1-260
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNEVPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKENPDLVI
CQYIDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKYQKEPPFLWMGYELHPNKWT
VQPIQLPEKESWTVNDIQKL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16E, L19I, E35D, M36I, R41K, K45R, D60E, Q61E, L63A, H69K, I72IM, L89M, I93L  
>2416| codons 1-99
PQITLWQRPLVSIKVEGQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYE
EIAIEICGKKAMGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013