Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1267 | CA23865 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | D4T+ 3TC | 23 |
| 3 | SQV+ D4T+ 3TC | 25 |
| 4 | SQV+ D4T+ ADV+ 3TC | 54 |
| 5 | D4T+ 3TC+ RTV+ SQV | 75 |
| 6 | ABC+ D4T+ DDI | 94 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14R, L19I, L63P, A71AV, T74TA |
| >CA23865| codons 1-99 PQITLWQRPVVTVRIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKVIGAVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L210LW, T215FY | K219KQ | K20R, V35VL, T39TA, K43KN, V60I, K104KN, K122KE, I135T, I142IV, S162CY, T200A, I202IV, Q207QE, A288AS, I293V |
| >CA23864| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICAELENEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKNSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKVEELREHLWRWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |