<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, K70KE, M184MV D67G, K219KEGR K101E, V106M, Y181YC, G190A   V35T, E36A, T39E, E40D, S48T, S68SG, W88S, L109LI, K122E, D123S, I135IL, E138EQ, I142IV, K166R, K173A, D177E, I178L, T200A, E204K, Q207D, R211K, F214L, V245Q, T286A, E291D, V292I, I293V, I329L  
>115| codons 1-332
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPV
FAIKRKGGTEWRKLVDFRELNKRTQDFSEVQLGIPHPAGLEKKKSMTVIDVGDAYFSVPL
DESFRKYTAFTIPSLNNQTPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAQNPELVI
CQYVDDLYVASDLEIGQHRAKIEKLRDHLLKWGLTTPDRKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20R, E35D, M36I, R41K, D60E, Q61E, H69K, L89M, I93L  
>115| codons 1-99
PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
EILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013