<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+LPV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V     V179D K20R, V35T, E36A, T39E, S48T, W88C, K102R, K103R, V118I, K122E, D123N, I135L, E138A, T139A, S162C, Q174K, T200A, Q207E, R211I, F214L  
>2032| codons 1-239
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKRRKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSLNNAAPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKKNPDIDI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLIWGLTTPDKKHQKEPPFLWMGYELHPDKW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, L76V, V82A L10F I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61N, L63H, H69K, L89I, I93L  
>2032| codons 1-99
PQITLWQRPFVTIKVEGQIREALLDTGADDTVLEDINLPGKWKPKLIGGIGGFVKVRQYD
NIHIEICGKKAIGTVVVGPTPANIIGRNILTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013