Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3929 | CA23857 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 34 |
| 2 | 3TC+AZT | 60 |
| 3 | 3TC+AZT+IDV | 36 |
| 4 | 3TC+AZT+IDV+RTV | 5 |
| 5 | 3TC+D4T+IDV+RTV | 5 |
| 6 | 3TC+D4T+NFV | 108 |
| 7 | APV+D4T+DLV | 54 |
| 8 | 3TC+APV+AZT | 78 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46L | L24LI, L33F, N88D | I13V, E34D, M36I, L63P |
| >CA23857| codons 1-99 PQITLWQRPLVTVKIGGQLKEALIDTGADNTVFDEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K103N | V60I, K122E, I135T, D177E, T200TA, R211K, Q278H, T286A, I293V, P294S |
| >CA23856| codons 1-299 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGAKALTEVVSLTEEA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |