<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+D4T+EFV+NVP 26
2 3TC+AZT+DDI+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215F   V106M, G190A F227L P4S, V21VI, V35T, T39E, E44D, S48T, K122E, D123N, K173T, Q174K, I178IL, T200TA, E203K, Q207E, H208HY, R211K, K223E, L228R, V245Q, D250X K49KT
>664| codons 1-260
PISSIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICEELEKDGKITTIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDLVI
YQYVDDLYVASDLEIGQHRAKIKELREYLWKWGFFTPDKKHQEEPPLRWMGYELHPDKWT
VQPIQLPEKXSWTVNDIQKL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L   T12S, I15V, L19I, K20R, E35D, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
>664| codons 1-99
PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEDINLPGKWKPKLIGGIGGFIKVRQYE
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Van Zyl, GU Trends in genotypic HIV-1 antiretroviral resistance between 2006 and 2012 in South African patients receiving first- and second-line antiretroviral treatment regimens. PLoS ONE, 2013