<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  R263RK K14R, L28I, V31I, V32I, K34KR, S39N, I60M, I72V, T112V, I113V, T124A, T125A, V126F, G134GS, K136Q, D167E, R187RK, V201I, I203M, N222K, R231RK, D232DN, K240R, V259VI, A265AT N144NY, H171HP, S283G
>THR15INT| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNIPPIIAREIVANCDKCQLKGEAMHGQVDCSPGM
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN
FTSAAFKAACWWASIQQEFGIPYYPQSQGVVESMNKELKKIIGQVREQAEPLKTAVQMAV
FIHNFKKKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQKFRVYYRDSKNPLWKGPAR
LLWKGEGAVVIQDNSDIKIVPRKKTKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12TI, I13V, K14KR, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M  
>THR15PRRT| codons 1-99
PQITLWQRPLVIVRIGGQQREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11R, V35T, T39L, K49R, V60I, K64KR, D121H, K122E, I135T, S162C, Q174H, D177E, V179I, T200I, Q207A, R211K L26LS
>THR15PRRT| codons 1-240
PISPIDTVPVRLKPGMDGPKVKQWPSTEEKIKALTEICLEMEKEGKISRIGPENPYNTPI
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKHNPEIII
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT

References
Author Title Citation
Jahanbakhsh, F Prevalence of transmitted HIV drug resistance in Iran between 2010 and 2011. PLoS ONE, 2012