Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5350 | CA23690 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 213 |
| 2 | DDI | 91 |
| 3 | D4T | 61 |
| 4 | AZT+DDC+IDV | 60 |
| 5 | 3TC+AZT+IDV | 17 |
| 6 | 3TC+D4T+NVP | 47 |
| 7 | ABC+RTV+SQV | 113 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82T, I84V, L90M | L33F, G73S | L10V, I13V, I15V, N37ND, K45R, I62IV, L63P, A71V |
| >CA23690| codons 1-99 PQITLWQRPVVTVKVGGQLKEALLDTGADDTVFEEMDLPGRWKPRMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPTNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70GR, M184MV, T215F | K219Q | V35T, T39A, V60I, T69N, K122E, I135T, T139M, G196E, A272P | E297H |
| >CA23689| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPI FAIKKKNSNGWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNEMPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKIEELRQHLLRWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTHEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |